leading technologies
for innovative medicine

Company Onco Genotest
develops technologies for personalized treatment of oncological diseases by investigation genomic data.
Our aim
is application of OMICs technologies and current knowledge of oncogenesis in clinical practice.

How molecular profiling of tumor can help to treat cancer?

Accumulation of mutations

in oncogenes and genes-suppressors can lead to developing of cancer by alteration of intracellular metabolism, proliferation, cell death and cellular interplay. Such cell's modifications are responsible for growth of tumor.

These mutations

have clinical significance for progress of disease, associated with effectiveness of different treatment options and, therefore, are regarded as biomarkers.

Biomarker is a result of analysis,

which has definite prognostic and predictive meaning. Today there are a lot of drugs on market, which target specific molecular changes (biomarkers) in cancer cells (target treatment). Furthermore, recent investigations demonstrate that effectiveness of standard chemotherapy also depends on molecular profile of tumor

The currently challenge is

not only in necessity of developing new therapeutic agents, but also in problems of sensible using different drugs for every patient and overcoming resistance to various treatment options.

Personalized medicine is

a new therapeutic approach involving the use of an individual’s genetic and epigenetic information, environment conditions and patient’s lifestyle to tailor drug therapy or preventive care. In oncology personalized treatment includes using tumor's molecular profile for diagnosis, creation of therapy plan and assessment of treatment effectiveness.

Tumor molecular profiling

Consultation

Consultation includes: indications for molecular-genetic analysis; collection of data about patient and anamnesis morbi; collection of samples or analysis (biopsy and liquid biopsy)

Confirmation of diagnosis

Histological confirmation of diagnosis

Development of molecular profile

Development of molecular profile (NGS; IHC)

Processing of data

Bioinformatic and system biology processing of data

Complex conclusion:

Complex conclusion: individual molecular profile, potential sensitive\resistance to different treatment options, clinical trials, mechanisms of cancerogenesis

Creation of complex molecular profile of tumor

Consultation

Confirmation of diagnosis

Development of molecular profile

Processing of data

Complex conclusion

Histological confirmation of diagnosis
Development of molecular profile (NGS; IHC)
Bioinformatic and system biology processing of data
Complex conclusion: individual molecular profile, potential sensitive\resistance to different treatment options, clinical trials, mechanisms of cancerogenesis
Consultation includes: indications for molecular-genetic analysis; collection of data about patient and anamnesis morbi; collection of samples or analysis (biopsy and liquid biopsy)

Bioinformatic platform

Comprehensive database

includes knowledge about all clinically significant biomarkers, clinical trials, pharmacogenomics and signal pathways. Database regularly updated from approved sources. All data is stored in cloud storage and good guarded.

Platform enables

to provide complex analysis of different types of biomarkers, including data about anamnesis morbi, histological characteristics of tumor, NGS, IHC and other diagnostic options

Special attention

was given to the most accurate detection of molecular alterations by using of the latest versions of bioinformatic software. By using of neural networks and deep learning we develop proprietary algorithm for analysis of associations between molecular profile of tumor and potential effectiveness of treatment.

Our unique platform

implements the principles of precision medicine and provides oncologists with wide summary of data for the best treatment option.

Products

OncoMind+

"OncoMind+" - personalized solution for selection of therapy for cancer patients. Personalized targeted therapy is selected based on molecular genetic tumor profiling, using next-generation sequencing technologies (NGS, average coverage 500x) and innovative bioinformatic data processing.

We know that each case is individual. Therefore,we will recommend the most optimal size of the genetic panel, taking into consideration each clinical case.

OncoMind

If you already have the results of molecular genetic analysis of the tumor (NGS or other testing), you can use our platform that provides unique methods of interpreting clinical and laboratory data. As a result of the analysis you will receive a report with review of molecular-genetic alterations in tumor cells, potential effective/noneffective drugs according to molecular profile of tumor, taking into consideration the latest international guidelines and clinical trials.

OncoMind

Stages

  • Bioinformatic and system-biology data processing implemented based on the latest international guidelines and clinical trials.
  • Report that contains information on the biomarkers examined in the analysis and their correlation with the effectiveness of use of various types of therapy and prognosis.
  • Access to test results in a user-friendly form by interactive platform Youroncohelp.
  • Consultation on the analysis: our experts will comment on the report formed on the basis of the interpretation of the genetic data and answer any of your questions.

Pricing

For more detailed information on the price of the service, please contact us by clicking the "order" button. Your request will be automatically forwarded to the manager who will contact you in the nearest future to clarify the information.

Order

OncoMind+

Advantages

"OncoMind+" is designed specifically to assist in personalized selection of therapy for cancer patients. This solution include:

  • Analysis of histology slides. Conducting of this analysis is recommended in the following cases:
    • Confirmation of diagnosis;
    • Assessment of the eligibility of biomaterial to further testing
  • Next generation sequencing (NGS): SNV, Ins/Del, CNV, fusion (size depends on NGS panel)
  • Complex bioinformatic and system-biology data processing:
    • review of molecular-genetic alterations in tumor cells;
    • clinical important biomarkers;
    • potential effective drugs;
    • prognostic important biomarkers - drugs toxicity, attendant prognostic factors.
  • Access to test results by interactive platform Youroncohelp
  • Consultation on the results of the analysis.

Pricing

For more detailed information on the price of the service, please contact us by clicking the "order" button. Your request will be automatically forwarded to the manager who will contact you in the nearest future to clarify the information.

Order

News

Our presentation at the conference

Partners

Contacts

Address

Russia, 125047, Moscow, 1-ya Brestskaya, 33

Treatment of cancer requires a team approach. We will be glad to communicate and create an interdisciplinary consilium for solving medical and scientific issues.

OncoMind Order

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OncoMind+ Order

Download the application, fill it and attach it to the form.